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Economic Evaluation in Genomic and Precision Medicine
Economic Evaluation in Genomic and Precision Medicine provides an in-depth examination of essential concepts, protocols and applications of economic evaluation in genomic and precision medicine.Contributions from leading international medical geneticists and health economists compile new ways to effectively assess the costs and outcomes of different genomic care pathways, implement cost-effective medical interventions, and enhance the value of genomic and precision healthcare.Foundational chapters and discipline-specific case studies cover topics ranging from the economic analysis of genomic trial design, to health technology assessment of next-generation sequencing, ethical aspects, economic policy in genomic medicine, and pricing and reimbursement in clinical genomics.
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Public Health Evaluation and the Social Determinants of Health
Compelling evidence shows health disparities are the result of inequalities in income, education, limited access to medical care, substandard social environments, and poor economic conditions.This book introduces these social determinants of health (SDOH), discusses how they relate to public health programs, and explains how to design and evaluate interventions bearing them in mind.Arguing that many public health programs fail to be as effective as they could be, because they ignore the underlying causes of health disparities, this important reference gives concrete examples of how evaluations focusing on the social determinants of health can alleviate health inequalities, as well as step-by-step guidance to undertaking them. This resource blends current research, existing data, and participatory evaluation methods.It is designed for teachers, students, practitioners, and policymakers interested in public health programming and evaluation. A Choice Recommended Title
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The Vitamins : Fundamental Aspects in Nutrition and Health
The Vitamins: Fundamental Aspects in Nutrition and Health, Sixth Edition presents both overviews and in-depth discussions of the sources, chemistry, metabolism and functions of these essential nutrients in physiology and health.Sections cover perspectives (history of discovery, general properties and impacts), individual Vitamins (their respective chemistries, metabolism), and their dietary sources and global needs.In addition, the inclusion and interpretation of recent clinical research findings relevant to all vitamins, particularly vitamins A, D, E, K, C, thiamin, folate and vitamin B12 is included, along with an expanded discussion on single-carbon metabolism), implications to neuropathies, and more.
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Realistic Evaluation
Realistic Evaluation shows how program evaluation needs to be, and can be bettered.It presents a profound yet highly readable critique of current evaluation practice, and goes on to introduce a `manifesto' and `handbook' for a fresh approach. The main body of this book is devoted to the articulation of a new evaluation paradigm, which promises greater validity and utility from the findings of evaluation studies.The authors call this new approach `realistic evaluation'.The name reflects the paradigm's foundation in scientific realist philosophy, its commitment to the idea that programmes deal with real problems rather than mere social constructions, and its primary intention, which is to inform realistic developments in policy making that benefit programme participants and the public.Ray Pawson and Nicholas Tilley argue with passion that scientific evaluation requires a careful blend of theory and method, quality and quantity, ambition and realism. The book offers a complete blueprint for evaluation activities, running from design to data collection and analysis to the cumulation of findings across programmes and onto the realization of research into policy.The argument is developed using practical examples throughout and is grounded in the major fields of programme evaluation. This book will be essential reading for all those involved in the evaluation process especially those researchers, students and practitioners in the core disciplines of sociology, social policy, criminology, health and education. `This book is a must for those engaged in the field, providing a fully illustrated text on evaluation with numerous examples from the criminal justice system.Unusually, it offers something for the academic, practitioner and student alike.I found Pawson and Tilley's latest work on evaluation an enjoyable and informative read.For myself their "realistic evaluation" clarified and formalised a jumbled set of ideas I had already been developing.Although not everyone will agree with the methodology proposed by the authors, this book is a valuable read as it will cause most of us at least to review our methodological stance' - International Journal of Police Science and Management`This is an engaging book with a strong sense of voice and communicative task.The voice is sometimes strident, but always clear. Its communicative qualities are evident equally in its structure: lots of signposting for the reader within and across chapters' - Language Teaching Research`This provocative, elegant and highly insightful book focuses on the effective incorporation of actual practice into the formulation of evaluation methodology.What a pleasure to read sentences like: "The research act involves "learning" a stakeholder's theories, formalizing them, and "teaching" them back to that informant who is then in a position to comment upon, clarify and further refine the key ideas".Pawson and Tilley have given us a wise, witty and persuasive account of how real practitioner experience might be encouraged to intrude on (and modify) researchers' concepts about program processes and outcomes.This holds important promise for achieving something that is devoutly to be wished: closer interaction among at least some researchers and some policy makers' - Eleanor Chelimsky, Past-President of the American Evaluation Association`This is a sustained methodological argument by two wordly-wise social scientists.Unashamedly intellectual, theoretically ambitious yet with a clear but bounded conception of evaluation.It is articulate, occasionally eloquent and always iconoclastic, whilst eschewing "paradigm wars".The Pawson and Tilley "realist" call to arms threatens to take no prisoners among experimentalists, constructivists or pluralists.It is the kind of book that clarifies your thoughts, even when you disagree with everything they say' - Elliot Stern, The Tavistock Institute
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Self-Healing Cementitious Materials : Technologies, Evaluation Methods, and Applications
Climate change is anticipated to have a major impact on concrete structures through increasing rates of deterioration and the impact of extreme weather events.The repair of any damage will be highly labor-intensive and expensive.Self-healing cementitious materials can enable the construction industry to mitigate these effects and move toward greater sustainability, safety, and increased cost savings and efficiency.This book: Examines concrete structures based on various materials with self-repair capability and their implications for future use in sustainable projects. Discusses advantages and design strategies of self-healing concretes. Covers several effective and detailed self-repair methods, with comparative analysis of the advantages and disadvantages of each method. Examines the use of various materials, including polymers and nanomaterials. Reviews factors affecting performance, properties, and applications. Delves into future directions and opportunities. Written for researchers, advanced students, and industry professionals, Self-Healing Cementitious Materials: Technologies, Evaluation Methods, and Applications offers a detailed view of an important emerging technology in materials science, civil engineering, and related fields.
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Program Evaluation : Embedding Evaluation into Program Design and Development
Program Evaluation: Embedding Evaluation into Program Design and Development provides an in-depth examination of the foundations, methods, and relevant issues in the field of evaluation.With an emphasis on an embedded approach, where evaluation is an explicit part of a program that leads to the refinement of the program, students will learn how to conduct effective evaluations that foster continual improvement and enable data-based decision making.This text provides students with both the theoretical understanding and the practical tools to conduct effective evaluations while being rigorous enough for experienced evaluators looking to expand their approach to evaluation.
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Methods for the Economic Evaluation of Health Care Programmes
The purpose of economic evaluation is to inform decisions intended to improve healthcare.The new edition of Methods for the Economic Evaluation of Health Care Programmes equips the reader with the necessary tools and understanding required to undertake evaluations by providing an outline of key principles and a 'tool kit' based on the authors' own experiences of undertaking economic evaluations. Building on the strength of the previous edition, the accessible writing style ensures the text is key reading for the non-expert reader, as no prior knowledge of economics is required.The book employs a critical appraisal framework, which is useful both to researchers conducting studies and to decision-makers assessing them.Practical examples are provided throughout to aid learning and understanding. The book discusses the analytical and policy challenges that face health systems in seeking to allocate resources efficiently and fairly.New chapters include 'Principles of economic evaluation' and 'Making decisions in healthcare' which introduces the reader to core issues and questions about resource allocation, and provides an understanding of the fundamental principles which guide decision making. A key part of evidence-based decision making is the analysis of all the relevant evidence to make informed decisions and policy.The new chapter 'Identifying, synthesising and analysing evidence' highlights the importance of systematic review, and how and why these methods are used.As methods of analysis continue to develop, the chapter on 'Characterising, reporting and interpreting uncertainty' introduces the reader to recent methods of analysis and why characterizing uncertainty matters for health care decisions. The fourth edition of Methods for the Economic Evaluation of Health Care Programmes has been thoroughly revised and updated, making it essential reading for anyone commissioning, undertaking, or using economic evaluations in health care, including health service professionals, health economists, and health care decision makers.
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The Natural Medicine Handbook – The Truth about the Most Effective Herbs, Vitamins, and Supplements for Common Conditions
When it comes to natural medicines, such as herbs, vitamins, and dietary supplements, you want to make sure you're getting the truth about what works, what is safe, and what is a waste of money.You need evidence-based, trustworthy, unbiased sources and studies so that you can make wise decisions for yourself and your family. In consultation with the experts at ConsumerLab.com and Natural MedicinesTM, Dr. Walt Larimore has combed the available research from around the globe to evaluate about 1300 natural medicines or interventions for more than 500 conditions or indications summarized in helpful charts and tables.This highly readable and reliable guide will tell you what natural medicines have proven to be both safe and effective while suggesting the best-value "Top Picks" for health issues such as- brain and heart health- digestive and immune health- energy and fatigue- losing weight- keeping hair, skin, and nails young- increasing the quality and length of your life- and many moreArranged topically so you can go directly to the information you need, this comprehensive, trustworthy guide is a resource you'll return to again and again. Praise for The Natural Medicine Handbook"I highly recommend this informative book.In it you will find reliable, independent evidence that will help inform your health-related decisions."--Dónal O'Mathúna, PhD"A much-needed and intensely evidence-based resource. . . . Anyone reading this book will gain the skills needed to ask and answer the right questions about whether to and how to incorporate natural medicines as part of their healthy lifestyle."--Reid B.Blackwelder, MD, FAAFP"An entirely digestible and ultimately useful guide for patients and practitioners alike."--Matthew A.Ciorba, MD"Navigating the landscape of herbs, vitamins, and supplements can be particularly complex and treacherous.Dr. Larimore's approach is direct and comprehensive and will certainly help numerous patients and their families make informed and safe decisions."--Jacob N.Hall, MD
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